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Hiroshi Nakano Selected Research

Therapeutics

5/2024Prognostic Factors and Impact of Therapeutic Intervention in Patients With Brain Metastases at the Initial Presentation.
3/2018Heart-type fatty acid binding protein as a prognostic factor in patients with exacerbated chronic obstructive pulmonary disease.
1/2018[A case of leptomeningeal carcinomatosis involving loss of eyesight after total gastrectomy for gastric cancer].
6/2013The aspartate aminotransferase to platelet ratio before chemotherapy predicts adverse events for FOLFOX and XELOX regimens including bevacizumab as the first-line therapy for stage IV, recurrent and metastatic colorectal cancer.
5/2011RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis.
3/2011Interleukin-28B acts synergistically with cisplatin to suppress the growth of head and neck squamous cell carcinoma.
1/2006Interleukin-21 triggers both cellular and humoral immune responses leading to therapeutic antitumor effects against head and neck squamous cell carcinoma.
12/2005Therapeutic efficacy of infliximab on active Crohn's disease under nutritional therapy.
11/2005[Carotid parameters measured by ultrasonography as a marker of atherothrombotic infarction and lacunar infarction in high risk elderly people].
1/2003Characteristics and prognosis of hepatocellular carcinoma detected in sustained responders to interferon therapy for chronic hepatitis C.

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Hiroshi Nakano Research Topics

Disease

30Neoplasms (Cancer)
05/2024 - 01/2002
18Stomach Neoplasms (Stomach Cancer)
11/2023 - 05/2007
16Type 2 Diabetes Mellitus (MODY)
01/2014 - 02/2002
14Neoplasm Metastasis (Metastasis)
08/2021 - 01/2002
12Inflammation (Inflammations)
01/2021 - 03/2003
10Gastritis
03/2014 - 01/2007
9Colorectal Neoplasms (Colorectal Cancer)
10/2021 - 01/2006
8Ulcerative Colitis
06/2009 - 11/2003
7Chronic Obstructive Pulmonary Disease (COPD)
01/2022 - 01/2014
6Hypercholesterolemia
01/2013 - 10/2006
6Infections
03/2012 - 01/2000
5Glucose Intolerance
01/2018 - 01/2006
5Squamous Cell Carcinoma of Head and Neck
04/2015 - 01/2006
4Pneumonia (Pneumonitis)
08/2022 - 01/2019
4Adenocarcinoma
03/2021 - 03/2007
4Ulcer
11/2019 - 01/2006
4Insulin Resistance
01/2018 - 01/2006
4Asthma (Bronchial Asthma)
10/2017 - 05/2016
4Hyperglycemia
06/2014 - 01/2006
4Atrophy
07/2009 - 03/2003
4Stomach Ulcer (Gastric Ulcer)
11/2008 - 01/2006
4Pancreatic Fistula (Pancreatic Fistulas)
03/2008 - 07/2003
3Pulmonary Emphysema
01/2022 - 01/2014
3Lung Neoplasms (Lung Cancer)
01/2021 - 01/2014
3Emphysema
01/2021 - 01/2014
3Obstructive Sleep Apnea
10/2020 - 02/2004
3Respiratory Sounds (Crackle)
10/2017 - 01/2016
3Lymphatic Metastasis
04/2015 - 06/2013
3Diabetes Mellitus
06/2014 - 11/2005
3Hypertension (High Blood Pressure)
09/2013 - 11/2005
3Splenomegaly
09/2013 - 06/2011
3Obesity
04/2012 - 07/2006
3Peptic Ulcer (Peptic Ulcers)
03/2012 - 09/2007
3Carcinogenesis
05/2010 - 06/2007
3Dyspepsia (Indigestion)
12/2009 - 03/2008
3Metaplasia
06/2009 - 03/2008
3Duodenal Ulcer (Curling's Ulcer)
06/2009 - 09/2007
3Hepatocellular Carcinoma (Hepatoma)
08/2007 - 01/2003
3Hypertrophy
07/2007 - 03/2003
3Crohn Disease (Crohn's Disease)
07/2006 - 11/2005
2Esophageal Squamous Cell Carcinoma
06/2021 - 01/2021
2Heart Failure
01/2021 - 03/2018
2Dehydration (Water Stress)
03/2019 - 11/2018
2Head and Neck Neoplasms (Head and Neck Cancer)
08/2017 - 01/2017
2Esophageal Neoplasms (Esophageal Cancer)
01/2017 - 03/2014
2Respiratory Hypersensitivity
01/2017 - 05/2016
2Thrombosis (Thrombus)
06/2016 - 03/2013
2Carcinoma (Carcinomatosis)
01/2016 - 10/2014
2Hypoglycemia (Reactive Hypoglycemia)
03/2015 - 01/2006

Drug/Important Bio-Agent (IBA)

10Glucose (Dextrose)FDA LinkGeneric
01/2013 - 01/2006
10AntralIBA
07/2009 - 01/2007
9Blood Glucose (Blood Sugar)IBA
01/2012 - 01/2006
6Oxygen (Dioxygen)IBA
01/2019 - 05/2005
6Proteins (Proteins, Gene)FDA Link
03/2018 - 11/2003
6colestimideIBA
01/2013 - 10/2006
5Nitric Oxide (Nitrogen Monoxide)FDA Link
10/2017 - 01/2010
5Codon (Codons)IBA
07/2009 - 01/2008
4Hexosaminidases (Hexosaminidase)IBA
06/2014 - 01/2012
4Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
03/2012 - 01/2006
3SmokeIBA
01/2022 - 01/2020
3Biomarkers (Surrogate Marker)IBA
07/2021 - 03/2018
3Polysaccharides (Glycans)IBA
11/2020 - 01/2007
3Indicators and Reagents (Reagents)IBA
01/2017 - 06/2002
3Cisplatin (Platino)FDA LinkGeneric
01/2017 - 03/2011
31,5-anhydroglucitolIBA
06/2014 - 10/2013
3NADPH Oxidases (NAD(P)H oxidase)IBA
12/2009 - 09/2008
3Mannose-Binding Lectin (Mannan-Binding Lectin)IBA
07/2009 - 01/2008
3Cyclooxygenase 1IBA
07/2008 - 09/2007
3Theophylline (Theon)FDA LinkGeneric
05/2008 - 10/2006
2InterferonsIBA
11/2023 - 01/2003
2LigandsIBA
01/2022 - 06/2013
2Chemokine CCL17IBA
01/2022 - 01/2021
2Pancreatic Elastase (Elastase)IBA
01/2022 - 01/2014
2MicroRNAs (MicroRNA)IBA
11/2021 - 07/2007
2DNA (Deoxyribonucleic Acid)IBA
11/2021 - 07/2008
2Messenger RNA (mRNA)IBA
11/2021 - 04/2015
2AntigensIBA
10/2021 - 01/2007
2CarbohydratesIBA
10/2021 - 08/2012
2Tn antigenIBA
10/2021 - 11/2020
2CytokinesIBA
01/2021 - 01/2006
2Anti-Bacterial Agents (Antibiotics)IBA
01/2021 - 03/2019
2Topoisomerase I InhibitorsIBA
01/2021 - 08/2007
2Capsules (Microcapsules)IBA
12/2018 - 05/2007
2Adrenal Cortex Hormones (Corticosteroids)IBA
03/2017 - 01/2017
2prednylidene (Pred)IBA
01/2017 - 05/2016

Therapy/Procedure

13Drug Therapy (Chemotherapy)
05/2024 - 08/2007
10Therapeutics
05/2024 - 01/2003
8Hepatectomy
09/2013 - 01/2002
7Pancreaticoduodenectomy
03/2021 - 01/2002
6Gastrectomy
11/2021 - 03/2007
4Activities of Daily Living (ADL)
03/2019 - 12/2005
4Glycemic Control
06/2014 - 04/2012
3Esophagectomy
08/2022 - 03/2014
3Immunotherapy
10/2021 - 01/2006
3Neoadjuvant Therapy
01/2021 - 06/2013
3Laparotomy
11/2017 - 06/2007
3Free Tissue Flaps
08/2017 - 03/2013
2Operative Surgical Procedures
01/2022 - 10/2014
2Intranasal Administration
01/2022 - 11/2007
2Continuous Positive Airway Pressure
10/2020 - 07/2011